KMID : 1140120050100020128
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Cancer Prevention Research 2005 Volume.10 No. 2 p.128 ~ p.133
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Increased Anticancer Effect of Kochujang (Korean Red Pepper Soybean Paste) Prepared with Garlic Powder Dried with Different Methods
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Kong Chang-Suk
Kim Su-Ok Jung Keun-Ok Kil Jeung-Ha Lee Sook-Hee Han Min-Soo Park Kun-Young
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Abstract
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The anticancer effects of methanol extracts from garlic dried differently and the dried garlic added kochujang (Korean red pepper soybean paste) were evaluated on AGS human gastric and HT-29 human colon adenocarcinoma cells by MTT assay. Freeze dried garlic was made from a whole bulb garlic and hot-air dried garlic were prepared from a whole bulb, sliced and chopped garlic at 70oC. Methanol extracts of the freeze dried garlic showed higher anticancer effects than those of hot-air dried garlic on AGS human gastric and HT-29 human colon adenocarcinoma cells. Among the hot-air dried garlic, sliced garlic showed the highest inhibition rate. The kochujang prepared with the freeze dried garlic showed higher anticancer effects than the kochujang with hot-air dried garlic on AGS human gastric and HT-29 human colon adenocarcinoma cells. Addition of the freeze dried garlic during kochujang preparation inhibited the growth of the cells in a concentration dependent manner. Addition of the dried garlics during kochujang preparation increased anticancer activities, especially freeze dried one was more effective.
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KEYWORD
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Kochujang, Garlic, Anticancer, MTT assay
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